Emergency Medicine Emergency Medicine · High Yield

Causes of Shock

Shock is defined as inadequate tissue perfusion resulting in cellular hypoxia. Classification into five types guides targeted resuscitation — treating the wrong type of shock with the wrong fluid can be fatal.

✦ The Mnemonic

"CHORD Classifies All Shock Types"

Cardiogenic · Hypovolaemic · Obstructive · Redistributive (septic/anaphylactic/neurogenic) · Distributive

C Cardiogenic Heart failure to pump; MI, arrhythmia, massive PE, myocarditis; cold clammy; raised JVP
H Hypovolaemic Blood/fluid loss; trauma, GI bleed, burns; cool peripheries; tachycardia; flat JVP
O Obstructive Outflow obstruction; tension pneumothorax, cardiac tamponade, massive PE; raised JVP + hypotension
R Redistributive — Septic Vasodilation + maldistribution; warm peripheries initially; high CO; source control essential
D Distributive — Anaphylactic/Neurogenic Anaphylaxis: urticaria, bronchospasm, angioedema; Neurogenic: warm + bradycardia post-SCI

📚 Clinical Breakdown

Haemorrhagic shock classification (ATLS): Class I (<15% blood loss, no symptoms), Class II (15–30%, anxiety, tachycardia), Class III (30–40%, confusion, hypotension), Class IV (>40%, lethargy, life-threatening). Normal BP is maintained until Class III — tachycardia is the earliest sign.

Cardiogenic vs obstructive: both have raised JVP. Distinguishing features: tamponade = pulsus paradoxus + muffled heart sounds + Beck's triad; tension pneumothorax = tracheal deviation + absent breath sounds + hyperresonance; cardiogenic = pulmonary oedema + S3 gallop.

Septic shock (Sepsis-3 definition): sepsis + vasopressor requirement to maintain MAP ≥65 mmHg despite adequate fluid resuscitation, and serum lactate >2 mmol/L. Hour-1 bundle: blood cultures → antibiotics → 30 mL/kg IV crystalloid → lactate reassessment.

Septic shock Sepsis-3 MAP <65 + vasopressors + lactate >2 despite fluids
Earliest sign haemorrhage Tachycardia (not hypotension)
Obstructive shock features Raised JVP + hypotension + absent pulmonary oedema
Anaphylaxis first treatment IM adrenaline 0.5 mg (1:1000) into lateral thigh

⭐ Clinical Pearl

Anaphylaxis: IM adrenaline 0.5 mg (1:1000) is the first and most important treatment — given immediately, into the lateral thigh, through clothing if needed. Antihistamines and steroids are adjuncts, NOT first-line. Biphasic reactions occur in up to 20% of cases — observe for minimum 6 hours. Prescribe an adrenaline auto-injector on discharge.

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