Large Intestine Parts
The large intestine is 1.5 m long and runs from the ileocaecal valve to the anal canal. Its ten segments have distinct anatomy, and knowing them enables accurate localisation of pathology.
✦ The Mnemonic
"Can Anyone Help Stop All Rectal Problems Resolving Anally"
Caecum · Appendix · Ascending · Hepatic flexure · Transverse · Splenic flexure · Descending · Sigmoid · Rectum · Anal canal
Clinical Breakdown
Distinguishing features of colon vs small bowel: colon has haustra (sacculations from taeniae coli), taeniae coli (three longitudinal muscle bands), and appendices epiploicae (fat tags). Small bowel has circular folds (valvulae conniventes) that cross the entire lumen.
The dentate line in the anal canal is the embryological boundary between endoderm (above) and ectoderm (below). Above: columnar epithelium, autonomic innervation (no pain), superior rectal venous drainage. Below: squamous epithelium, somatic innervation (pain), inferior rectal venous drainage. This distinction explains why internal haemorrhoids are painless and external haemorrhoids are painful.
Colorectal cancer predominantly affects the rectum and sigmoid (60%). The left colon (descending and sigmoid) presents with altered bowel habit and rectal bleeding; the right colon (ascending, caecum) presents insidiously with iron-deficiency anaemia and weight loss due to blood loss into the large lumen.
⭐ Clinical Pearl
McBurney's point: the surface marking of the appendix base — one-third of the way from the ASIS to the umbilicus on the right side. Maximal tenderness here, along with Rovsing's sign (palpation of the left iliac fossa produces pain in the right), supports the diagnosis of appendicitis.