Nervous System Anatomy · Neurology

Meningeal Layers

The three meningeal layers protect the brain and spinal cord. The spaces between them are the sites of clinically critical haemorrhages — each with a distinct mechanism, CT appearance, and management.

✦ The Mnemonic

"Delicate Artful Protection — Dura, Arachnoid, Pia"

Dura mater · Arachnoid mater · Pia mater — with epidural, subdural, subarachnoid spaces

Dura Dura Mater Tough outer layer; two layers: periosteal + meningeal; folds form falx cerebri, tentorium cerebelli
EDSp Epidural Space Between dura and skull; contains middle meningeal artery; site of extradural haematoma
Arachnoid Arachnoid Mater Middle layer; spider-web trabeculae; avascular; CSF flows in subarachnoid space below
SDSp Subdural Space Between dura and arachnoid; bridging veins cross it — torn → subdural haematoma
Pia Pia Mater Innermost; closely adheres to brain surface; follows gyri and sulci; has no free surface
SAS Subarachnoid Space Between arachnoid and pia; filled with CSF; site of berry aneurysm rupture → SAH

📚 Clinical Breakdown

The dura has two layers in the skull: the outer periosteal layer (adherent to skull) and the inner meningeal layer. These separate at the dural sinuses (superior sagittal, transverse, sigmoid). The dura folds inward to form: falx cerebri (between hemispheres), tentorium cerebelli (between cerebrum and cerebellum), and the diaphragma sellae (roof of pituitary fossa).

Extradural haematoma: arterial bleed (usually middle meningeal artery from temporal bone fracture). Classic 'lucid interval': brief loss of consciousness, recovery, then progressive deterioration as the haematoma expands. Biconvex (lens-shaped) on CT — does not cross suture lines. Surgical emergency — burr hole/craniotomy.

Subdural haematoma: venous bleed from torn bridging veins (cortical veins crossing the subdural space). More common in elderly, alcoholics, patients on anticoagulants. Crescent-shaped on CT — follows brain surface and crosses suture lines. Acute (<3 days), subacute (3–21 days), or chronic (>21 days) — chronic SDH appears hypodense on CT.

Extradural haematoma Arterial (MMA); biconvex; lucid interval
Subdural haematoma Venous (bridging veins); crescent; crosses sutures
SAH appearance Blood in cisterns/sulci; worst headache ever
Falx cerebri Dural fold between hemispheres

⭐ Clinical Pearl

Uncal herniation: a supratentorial mass displaces the uncus (medial temporal lobe) through the tentorial notch, compressing CN III (dilated pupil), the posterior cerebral artery (ipsilateral occipital infarct), and the midbrain (Duret haemorrhages — secondary brainstem haemorrhage). The sequence: unilateral pupil dilation → decreasing consciousness → bilateral motor signs → death.

← Circle of Willis